Biodegradable polymers based on polylactide (PLA) and its co-polymers polylactide-co-glycolide (PLGA) were successfully spray dried with the Mini Spray Dryer B-290. Process parameters are found to prepare spherical particles with a smooth or structured surface.

A literature review demonstrates the feasibility to encapsulate different drugs in biodegradable microspheres for controlled drug delivery systems. Spray dried microparticles have a suitable size and shape for new application fields in pulmonary therapy, cancer treatment or medical devices.